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In 2005, a black box warning was put on the paxil label to caution against use during pregnancy due to the increased risk of cardiac defects.

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Therefore, the physician who elects to prescribe paxil cr for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient see dosage and administration .

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This warning came after glaxo smith kline, the maker of paroxetine paxil , failed to make public three studies it conducted in 2003 showing an increase in suicidal thinking in children who took the drug compared to those taking dummy placebo pills.

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Paxil cr the cr version are coated with a substance that allows them to be slowly released over a 24 hour period; hence being called controlled release.

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